After completing the review of video 1 materials, students will be able to:

• Determine populations that would benefit from organic acid testing
• Determine conditions that may benefit from organic acid testing
• Overview of main points of what organic acids test for
• Clarify to individuals on how to prepare for the test and procedure for specimen collection
• Determine particular confounders that may impact test results

After completing the review of module 2 materials, students will be able to:

• Recognize B complex vitamin deficiencies and enzyme polymorphism from the alpha-keto acids
• Recognize hypometabolic states from alpha-keto acid patterns
• Recognize confounders that may affect vitamin marker test results
• Recognize vitamin patterns that indicate possible cell membrane fluidity impairment
• Identify B12 metabolism markers
• Develop treatment regimens for vitamin deficiencies
• Identify patterns of the specific nutrient deficiency impairing methylation

After completing the review of module 3 materials, students will be able to:

• Summarize the biochemical steps of beta oxidation of fatty acids.
• Identify nutrient deficiencies indicated with elevations of adipate, suberate, and ethylmalonate.
• Identify nutrients needed for carnitine synthesis.
• Identify confounders of elevated adipate, suberate, and ethylmalonate.
• Identify origins of very low adipate and suberate, and ethylmalonate.
• Recognize patterns indicating polymorphisms in the beta-oxidation of fatty acid metabolism.
• Recognize patterns that indicate hypometabolic states.

After completing the review of module 4 materials, students will be able to:

• Summarize the catecholamine biochemical pathway.
• Identify and evaluate neurotransmitter organic acid patterns.
• Evaluate neurotransmitter ratios.
• Identify symptoms of low catecholamines.
• Develop a treatment plan for neurotransmitter imbalances based on organic acid evaluation.
• Evaluate and identify common polymorphisms involved in the catecholamine biochemical pathway.

After completing the review of module 5 materials, students will be able to:

• Recognize organic acid patterns in the Kynurenine pathway
• Identify and evaluate confounders of elevated 5-HIAA marker
• Summarize the Kynurenine biochemical pathway
• Evaluate the impact of diet to Kynurenine pathway patterns
• Summarize the biochemical pathways of tryptophan metabolism
• Connect tryptophan metabolism to brain and immune health
• Recognize patterns that may indicate dysbiosis
• Recognize patterns that may indicate hypometabolic states
• Evaluate ratios of Kynurenine markers
• Quantify B6 deficiency
• Recognize patterns that indicate neuroinflammation

After completing the review of module 6 materials, students will be able to:

• Evaluate lactate and pyruvate patterns
• Summarize the main energetic flux of glycolysis
• Summarize the Pyruvate Dehydrogenase Complex
• Develop treatment options for pyruvate and lactate imbalances
• Identify and evaluate conditions involved in lactate elevations
• Identify and evaluate conditions involved in Beta-Hydroxybuterate elevations
• Evaluate and connect diet impact on lactate/pyruvate patterns

After completing the review of module 7 materials, students will be able to:

• Identify hypometabolic states in the organic acids
• Recognize and evaluate cell regulator markers
• Determine the energetic flux of the TCA
• Recognize mitochondria oxidative stress patterns
• Summarize the Cell Danger Response Cycle
• Connect energy production to immune activation
• Recognize anapleresis patterns
• Recognize and evaluate patterns that indicate hypoxia
• Evaluate and develop a treatment plan for 3-Hydroxy-3-Methylglutarate (HMG) patterns
• Summarize conditions that restrict the electron transport chain flux

After completing the review of module 8 materials, students will be able to:

• Recognize markers for chronic pH renal balancing
• Identify and evaluate patterns of the Tricarboxylic acids
• Connect citric acid markers to immune function
• Explain the negative feedback pathways of elevated citric acid
• Recognize problems with Complex II as related to TCA
• Explain how to use alpha-ketoglutarate as a surrogate marker for systemic pH
• Recognize anaplerotic filling of the Citric Acid Cycle
• Recognize a pattern of functional CoQ10 deficiency

After completing the review of module 9 materials, students will be able to:

• Be able to define free radicals
• Identify and evaluate oxidative damage and detoxification markers
• Recognize mitochondria antioxidants
• Understand the antioxidant recycling pathway
• Predict glutathione status
• Develop an appropriate antioxidant treatment plan

After completing the review of module 10 materials, students will be able to:

• Identify organic acid dysbiosis markers
• Recognize excessive bacteria action on tryptophan
• Evaluate functional B5 sufficiency through benzoate and Hippurate patterns
• Recognize patterns of phase 2 detoxification overload
• Evaluate phenyl acid markers
• Relate Tricarballyate to bile
• Evaluate symptoms of dysbiosis
• Develop a plan for microbial overgrowth